Richard Lewis interrupted Peter Sagal several times when Peter was trying to read his introduction, which lead to hilarity. Also, while Richard Lewis was on the phone, his breathing into the phone was quite noticeable and that lead to a bit of laughing and a good amount of bantering.
Bill Kurtis accepted Brian Babylon's answer of "atmosphere" for a Lightning Fill-in-the-Blank question which had the appropriate answer of "ozone layer". The edited version of the show only included six Lightning Fill-in-the-Blank questions for Brian, in which he answered two correctly. The third answer would have been for one of the two questions that got edited out.