Peter and Mara Sagal welcomed their new baby, Theodore, on 2023-01-28, and Peter Grosz is filling in as guest host.

Zainab Johnson answered her 5th Lightning Fill-in-the-Blank question with "Titanic" but Peter Grosz gave her a hint by saying "Same director". Zainab changed her answer to "Avatar" and got credit for the answer.

Geena Davis initially chose "A" for her first Not My Job question; but, after some hesistation from Tom Papa, she changed her answer to "B", the correct answer. After Tom read all three choices for the third Not My Job question, many in the audience shouted "B". Geena chose "B" and it was the correct answer.

After Hari Kondabolu finished his set of Lightning Fill-in-the-Blank questions, Tom asked Bill Kurtis if Hari did well enough to win. At least in the radio/podcast edit of the show, Bill did not state how many questions Hari answered correctly. The score reflects the number of questions Hari answered correctly on the radio/podcast edit: three.

Not My Job guest Rosie Perez had previously been on Wait Wait... Don't Tell Me! as a panelist on the show that aired on 2014-05-31. Rosie initially chose "A" for her first Not My Job question but Alzo Slade nudged her to change her answer. Rosie changed her answer to "B", which was correct. Rosie asked for a hint for her third Not My Job question and Alzo responded with "Yes. More than one of them are correct." Rosie answered "all the above" and was correct; as, it was another instance where all 3 of the choices for the third Not My Job question were correct.

The Not My Job segment with Stephen Colbert was from the show that aired on 2017-02-11 with Glynn Washington as the guest scorekeeper.

The Not My Job segment with Rob Reiner was from the show that aired on 2012-06-13 with Peter Grosz as the guest host.