After Peter asked if anyone had followed the meeting between President Bush, Israeli Prime Minister Ehud Olmert and Chairman of the Palestinian National Authority Mahmoud Abbas, and Adam smartly replying "religiously", an audience member booed. This led to a great reaction from the panelists, with Adam retorting "What? ... Booed that early" and Amy cracking up.

Dana Perino is the second White House Press Secretary from the Bush Administration to appear on the show.

During the Listener Limerick Challenge round, one of the answers dealt with a computer program that interacts with people on Russian dating/romance sites. Upon hearing that, Amy twice cried out "No!" Paula had a lot of fun and ranted about the "love chat" bit. After Carl stated that the listener had correctly completed the three limericks, Paula exclaimed, "Brent was a genius!"