During the Not My Job segment, Roxanne Roberts mentioned that her son had been downloading and listening to various songs purportedly made by "Weird Al" Yankovic, but weren't. This caused "Weird Al" to say that one of them, about changing restroom signs, was not his. This led to a bit of embarrassment for Roxanne.

Roxanne had another bit of geekdom embarrassment when she confused Wookies as being in Star Trek. Peter had to correct Roxanne.

At the end of the Roxanne's Lightning Fill-in-the-Blank round, Peter stated that he thought about not giving Roxanne the last point as he kind of wanted Paula Poundstone to tie with Roxanne. Peter's conscience kicked in and gave the win to Roxanne.

Although Mo Rocca is a regular guest judge on "Iron Chef America", he did not appear as a panelist with Iron Chef Batali

In the Lightning Fill-in-the-Blank round, when Tom Bodett was asked what was the name of a California energy bill requiring people to use more efficient lighting, Tom responded with "We'll turn off the lights for you"; which is a play on Tom's Motel 6 advert tagline.

During the Not My Job segment, the producers aired a phone call received by Phil Bronstein's editors that referred to a newspaper headline about "pilotless drones" in which the caller went on a rant about "pilotless drones" are "drones".

Paula mentions "IHOP"; Tony Snow gets "caught" with an inconsistency (running into a tree while at President Bush's ranch) and faux-stumped when asked if President Bush listens to the show

For Amy Dickinson's last Lightning Fill-in-the-Blank question, discussing birth control for squirrels, Adam Felber gave the classic line, "Straight Talk About Nuts".

Justice Stephen Breyer is the first Supreme Court Justice to appear on a game show.

Several members of audience chanted "Luuuuuuke" when Luke was introduced by Peter; Paula mentions "IHOP" again; hilarious interaction between the panelists, Peter and Justice Breyer including discussion about his robe.

Another hilarious bluff by Mo, in which the listener contestant is from the same city as referenced in Mo's bluff. When asked what two spiders did during Mo's Lightning Fill-in-the-Blank round, Mo answered, in his unique manner, "knife fight!". The answer was "snuggling", to which Mo came back with "that's a lot of snuggling!"

The answer to Tom's last Lightning Fill-in-the-Blank question is the whole "Peepers The Duck" being dropped during a failed shoplifting gateway at a Linen 'N Things store. Hilarity ensued.

In response to the number of great-grand children and great-great-grand children that singer Don Ho had, Peter described them as "nappy bottomed Hos" as a pun on Don Imus's slur

Paula dishes out some negativity in regards to Cleveland, Ohio. This was brought up in 2008-02-23 during the interview with Drew Carey. Sue Ellicott's last regular appearance?

The first caller is Jimmy Jellinek, the editor-in-chief of Maxim.

Peter starts the show with Carl Kasell's on-air Freudian Slip by accidentally calling Monica Goodling, "Monica Lewinsky", then quickly correcting himself mid-word

Several members of audience chanted "Luuuuuuke" when Luke was introduced by Peter

Wait Wait... Don't Tell Me! visits Portland, Oregon for the second time.

After Patrick Fitzgerald was not able to answer two or more Not My Job questions correctly, an "appeal" was filed and Patrick won the game even with only one correct answer.

Limited audience chanting of "Luuuuuuke", in which Luke retorts that for each second of chanting would be one less second that Mo Rocca can make jokes. Tom Bodett finished his Bluff the Listener story with his famous "We'll leave the light on for you" tagline from his Motel 6 adverts.

Limited audience chanting of "Luuuuuuke"

Deputy White House Press Secretary Dana Perino was called in regards to Rove's opinion of Barney (President Bush's dog), Bob Saget gets bleeped

Peter admitted on the 2007-09-22 show that Paula Poundstone actually had 5 correct answers during the Lightning Fill-in-the-Blank round, rather than the 4 that Peter/Korva gave her credit for. Paula's score for this show reflects the incorrect score since it cannot be retroactively changed.

After Kyrie guessed "a cat" in her last Lightning Fill-in-the-Blank round question, Mo made several meowing sounds in response.

Peter admitted that they had robbed Paula of 2 points in the 2007-09-01 show and will "right the wrong" on this show; Peter predicted at the beginning of the show that it will be a good day for Paula. Paula got enough questions correct in the Lightning Fill-in-the-Blank round without any "additional assistance".

Amy Dickinson said that she didn't think she had won before and Peter was doubtful of that. Amy had tied for first at least seven times and won outright at least twice in 2010: 2010-02-03 and 2010-03-10.

The name of the Bluff the Listener round is "We'll Leave the Light on for You", which is the tagline used by panelist Tom Bodett's Motel 6 adverts, though Tom was not one of the panelists for this show.

Paul Provenza's had his first win on the show

Paula was a bit jealous about the court and lawyer crackdown in Pakistan, particularly that the lawyers were being hit with sticks. Roxanne asks Paula, "spend a lot of times around lawyers, huh?". This lead to a little laughter when the listener playing the Listener Limerick Challenge said that she was a lawyer.

Peter went a bit too far with conjugations of the Hebrew neologism "le condel", with Charlie threatening Peter if he did anymore conjugations.

When Paula had a hard time coming up with "Ho, ho, ho!", Peter and the other panelists gave her interesting hints about what mall Santas can no longer say in Australia. The entire bit got really funny when Paula went down the route of what Don Imus said to got him kicked off of the air.

The podcast version of the show Listener Limerick Challenge and Lightning Fill-in-the-Blank duplicated.wywy

This show is about the same as the 2006-08-05 show, with the exception of Brian Williams being the first Not My Job segment rather than Barack Obama.

After Peter asked if anyone had followed the meeting between President Bush, Israeli Prime Minister Ehud Olmert and Chairman of the Palestinian National Authority Mahmoud Abbas, and Adam smartly replying "religiously", an audience member booed. This led to a great reaction from the panelists, with Adam retorting "What? ... Booed that early" and Amy cracking up.

Dana Perino is the second White House Press Secretary from the Bush Administration to appear on the show.

During the Listener Limerick Challenge round, one of the answers dealt with a computer program that interacts with people on Russian dating/romance sites. Upon hearing that, Amy twice cried out "No!" Paula had a lot of fun and ranted about the "love chat" bit. After Carl stated that the listener had correctly completed the three limericks, Paula exclaimed, "Brent was a genius!"